| Description | Egis-11150 is an anti-neuropathy compound with pro-cognitive effects. |
| In vitro | EGIS 11150 （200 nM） 在体外海马体的 CA1 区域产生了稳健、持续的振荡节律 .[2] |
| In vivo | Egis-11150（0.01-0.3 mg/kg，ip.）在所有检查的精神分裂症临床前小鼠模型中都有效。[1] |
| molecular weight | 405.85 |
| Molecular formula | C19H21ClFN5O2 |
| CAS | 494861-87-9 |
| Storage | Powder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice. |
| References | 1. Gacsályi I, et al.Antoni FA. Egis-11150: a candidate antipsychotic compound with procognitive efficacy in rodents. Neuropharmacology. 2013 Jan;64:254-63. 2. Spedding M, et al. Phenotypical Screening on Neuronal Plasticity in Hippocampal-Prefrontal Cortex Connectivity Reveals an Antipsychotic with a Novel Profile. Cells. 2022 Mar 31;11(7):1181. |