| Description | (E/Z)-Squalene ((E/Z)-AddaVax) regulates intracellular reactive oxidant species (ROS) production and induces apoptosis and necrosis in a concentration and time-dependent manner. (E/Z)-Squalene accumulates in the liver and lowers hepatic cholesterol and triglycerides. |
| In vitro | (E/Z)-Squalene (0-50 μ M) 在人类乳腺上皮细胞 (MCF10A) 中，通过减少细胞内ROS水平，防止H2O2引起的氧化损伤，并保护细胞免受DNA氧化损害。[1] |
| Synonyms | (E/Z)-Super Squalene, (E/Z)-AddaVax |
| molecular weight | 410.72 |
| Molecular formula | C30H50 |
| CAS | 7683-64-9 |
| Storage | Powder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice. |
| Solubility | DMSO: 50 mg/mL (121.7 mM) |
| References | 1. Lou-Bonafonte JM, et al. Current Insights into the Biological Action of Squalene. Mol Nutr Food Res. 2018;62(15):e1800136. |