| Description | Naringenin chalcone (Isosalipurpol) has antiallergic activity Naringenin chalcone suppresses asthmatic symptoms by inhibiting Th2 cytokine production from CD4 T cells. Naringenin chalcone is a potent tomato flavonoid that improves adipocyte metabolic functions and exerts insulin-sensitizing effects by activating an adiponectin-related pathway. Naringenin chalcone exhibits anti-inflammatory properties by inhibiting the production of proinflammatory cytokines in the interaction between adipocytes and macrophages, may be useful for ameliorating the inflammatory changes in obese adipose tissue. |
| Synonyms | Isosalipurpol, 柚皮苷查尔酮, Chalconaringenin, trans-2'4'6'4-tetrahydroxychalcone, 柚皮素查耳酮 |
| molecular weight | 272.25 |
| Molecular formula | C15H12O5 |
| CAS | 73692-50-9 |
| Storage | Powder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice. |
| Solubility | DMSO: 49 mg/mL (180 mM) Chloroform, Dichloromethane, Ethyl Acetate, Acetone, etc.: Soluble |
| References | 1. Horiba T , Nishimura I , Nakai Y , et al. Naringenin chalcone improves adipocyte functions by enhancing adiponectin production[J]. Molecular & Cellular Endocrinology, 2010, 323(2):208-214. |