| Description | Apronal (Apronalide) has the hypnotic and sedative capacity and can be used for studies about neuropsychiatry disorders. |
| In vivo | 固定药疹和粘膜皮肤眼综合征已因Apronal[1]报告。Apronal不仅增加了动物肝脏和尿液中的卟啉含量，而且导致肝脏显著的绿色色素沉着。长期使用高剂量Apronal治疗的大鼠能够恢复良好，并将测量参数值恢复至正常。由长期应用Apronal产生的损伤，大鼠能够耐受并且是可逆的[2]。 |
| Synonyms | Apronalide, Allylisopropylacetylurea, 丙戊酰脲 |
| molecular weight | 184.24 |
| Molecular formula | C9H16N2O2 |
| CAS | 528-92-7 |
| Storage | Powder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice. |
| Solubility | DMSO: 145 mg/mL (787.02 mM), Sonication is recommended. |
| References | 1. Fujimoto Y, et al. Fixed drug eruption due to allylisopropylacetylurea. Contact Dermatitis. 1993 May;28(5):282-4. 2. Rentsch G, et al. The effect of prolonged administration of allylisopropylacetylurea to rats on cytochrome P-450 and other liver haemoproteins. Xenobiotica. 1976 Mar;6(3):151-7. |