Description | Duoperone is a neuroleptic agent. Duoperone shows antiemetic activity in animal models. |
In vivo | Duoperone在小鼠聚集状态下预处理时间在一小时至七天间,可阻断d-amphetamine的致死作用。具有单侧尾状核损伤的小鼠服用ARR-6646后可抑制由Apomorphine引起的旋转行为。与chlorpromazine相比.ABR-6646可引起大鼠僵直,其效应的起始时间推迟,持续时间延长。[1] |
molecular weight | 514.58 |
Molecular formula | C28H26F4N2OS |
CAS | 62030-88-0 |
Storage | Powder: -20°C for 3 years | In solvent: -80°C for 1 year |
Solubility | DMSO: 12 mg/mL (23.32 mM) |
References | 1. Johnson DN, et al. AHR-6646: a new, long-acting neuroleptic. Prog Neuropsychopharmacol. 1979;3(5-6):513-20. |