| Description | DprE1-IN-9 (compound B18) is an efficient reversible inhibitor of DprE1, interacting with the enzyme's receptor cavity. It exhibits potent antimycobacterial properties, demonstrating activity against both non-pathogenic H37Ra (MIC=0.18 µg/mL) and pathogenic strains, including H37Rv, as well as clinical MDR and XDR isolates [1]. |
| molecular weight | 434.45 |
| Molecular formula | C22H25F3N4O2 |
| CAS | 2906099-98-5 |
| Storage | Powder: -20°C for 3 years | In solvent: -80°C for 1 year |