| Description | DMA is a fluorescent agent (λex=340 nm, λem=478 nm). |
| In vitro | 在MCF7的情况下,DMA的IC50观察值为5.3 μM。而在HeLa的情况下,DMA的IC50确定值为3.4 μM。 |
| Target activity | MCF-7 cells:5.3 μM (IC50), HeLa cells:3.4 μM (IC50) |
| molecular weight | 468.55 |
| Molecular formula | C27H28N6O2 |
| CAS | 188860-26-6 |
| Storage | keep away from direct sunlight | Powder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice. |
| Solubility | DMSO: 13 mg/mL (27.75 mM) |
| References | 1. Singh M, et al. Synthesis and biological activity of novel inhibitors of topoisomerase I: 2-aryl-substituted 2-bis-1H-benzimidazoles. Eur J Med Chem. 2011 Feb;46(2):659-69. |