PeptideDB

DMA

CAS No.: 188860-26-6

DMA is a fluorescent agent (λex=340 nm, λem=478 nm).
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Description DMA is a fluorescent agent (λex=340 nm, λem=478 nm).
In vitro 在MCF7的情况下,DMA的IC50观察值为5.3 μM。而在HeLa的情况下,DMA的IC50确定值为3.4 μM。
Target activity MCF-7 cells:5.3 μM (IC50), HeLa cells:3.4 μM (IC50)
molecular weight 468.55
Molecular formula C27H28N6O2
CAS 188860-26-6
Storage keep away from direct sunlight | Powder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice.
Solubility DMSO: 13 mg/mL (27.75 mM)
References 1. Singh M, et al. Synthesis and biological activity of novel inhibitors of topoisomerase I: 2-aryl-substituted 2-bis-1H-benzimidazoles. Eur J Med Chem. 2011 Feb;46(2):659-69.