| Description | Amino-PEG8-amine is a pegylated based PROTAC linker that can be used in the synthesis of PROTACs. It is a conjugate PEG derivative containing two amino (NH2) groups. |
| In vitro | PROTACs通过利用细胞内的泛素-蛋白酶体系统，有选择性地降解目标蛋白质。它们由两个不同的配体构成，通过一个连接器连接。一个配体与目标蛋白质结合，另一个则与E3泛素连接酶结合。[1] |
| molecular weight | 412.52 |
| Molecular formula | C18H40N2O8 |
| CAS | 82209-36-7 |
| Storage | Powder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice. |
| References | 1. Lepage ML, et al. Design, synthesis and photochemical properties of the first examples of iminosugar clustersbased on fluorescent cores. Beilstein J Org Chem. 2015;11:659-667. |