| Description | Dim16, a dual inhibitor of PCSK9/HMG-CoAR, demonstrates potent activity with an IC50 of 19 nM against PCSK9 and significantly impedes PCSK9-LDLR interaction with an IC50 of 0.8 nM, leading to an enhanced LDL uptake in HepG2 cells [1]. |
| molecular weight | 583.55 |
| Molecular formula | C29H38IN5 |
| CAS | 2743448-32-8 |
| Storage | Powder: -20°C for 3 years | In solvent: -80°C for 1 year |