| Description | DIM-C-pPhOCH3 (C-DIM5) is a Nerve Growth Factor-Induced Bα (NGFI-Bα, Nur77) agonist |
| In vitro | 在体外环境下，该化学化合物能够诱导癌症细胞系发生凋亡。 |
| Target activity | Nur77:NA |
| Synonyms | C-DIM5 |
| molecular weight | 352.43 |
| Molecular formula | C24H20N2O |
| CAS | 33985-68-1 |
| Storage | Powder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice. |
| Solubility | DMSO: 35.24 mg/mL (100 mM) |
| References | 1. Bridi MS,etal.Pharmacological Activators of the NR4A Nuclear Receptors Enhance LTP in a CREB/CBP-Dependent Manner.Neuropsychopharmacology. 2017 May;42(6):1243-1253. 2. Chintharlapalli S,etal.Activation of Nur77 by selected 1,1-Bis(3'-indolyl)-1-(p-substituted phenyl)methanes induces apoptosis through nuclear pathways.J Biol Chem. 2005 Jul 1;280(26):24903-14. |