| Description | diABZI STING agonist-1 is a selective and potent interferon gene-stimulating receptor (STING) agonist with potential antitumor and anti-inflammatory activity for the study of cancer. |
| In vivo | 在 Wild 和 Sting -/- C57Blk6 小鼠中，diABZI STING agonist-1 ( 2.5 mg/kg ;皮下注射; 2.5 mg/kg)可激活野生型小鼠分泌 IFN β、IL-6、TNF 和 CXCL1，但对 Sting -/-小鼠无激活作用[1]。 |
| molecular weight | 849.94 |
| Molecular formula | C42H51N13O7 |
| CAS | 2138299-33-7 |
| Storage | Powder: -20°C for 3 years | In solvent: -80°C for 1 year |
| Solubility | H2O: < 1 mg/mL (Insoluble) DMSO: 80 mg/mL (94.12 mM), Sonication is recommended. |
| References | 1. Ramanjulu JM, et al. Design of amidobenzimidazole STING receptor agonists with systemic activity. Nature. 2018 Nov 7. |