| Description | DHFR-IN-2 (compound 4e) is a potent and uncompetitive inhibitor for MtDHFR with an IC 50 of 7 μM. The enzyme dihydrofolate reductase from M.tuberculosis (MtDHFR) has a high unexploited potential to be a target for new drugs against tuberculosis (TB), due to its importance for pathogen survival. DHFR-IN-2 can be used for tuberculosis (TB) research [1]. |
| molecular weight | 227.26 |
| Molecular formula | C14H13NO2 |
| CAS | 331942-46-2 |
| Storage | Powder: -20°C for 3 years | In solvent: -80°C for 1 year |