| Description | Demeclocycline hydrochloride (Declomycin) is a TETRACYCLINE analog having a 7-chloro and a 6-methyl. Because it is excreted more slowly than TETRACYCLINE, it maintains effective blood levels for longer periods of time. |
| Synonyms | 地美环素, Declomycin, Clortetrin, 盐酸地美环素, Detravis, Demeclocycline HCl |
| molecular weight | 501.32 |
| Molecular formula | C21H21ClN2O8·HCl |
| CAS | 64-73-3 |
| Storage | Powder: -20°C for 3 years | In solvent: -80°C for 1 year |
| Solubility | Ethanol: < 1 mg/mL (insoluble or slightly soluble) H2O: 9 mg/mL (17.97 mM) DMSO: 50 mg/mL (99.74 mM) |
| References | 1. Imming P, et al. Nat Rev Drug Discov. 2006 Oct;5(10):821-34. |
| Citations | 1. Zhang H, Liang B, Sang X, et al.Discovery of Potential Inhibitors of SARS-CoV-2 Main Protease by a Transfer Learning Method.Viruses.2023, 15(4): 891. |