| Description | Delucemine Hydrochloride (Delucemine) is a polyamine NMDA receptor antagonist used in the study of neurological disorders such as depression and Alzheimer's disease. |
| Synonyms | NPS 1506, Delucemine, Delucemine HCl, NPS1506, NPS-1506 |
| molecular weight | 297.77 |
| Molecular formula | C16H18ClF2N |
| CAS | 186495-99-8 |
| Storage | Powder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice. |
| References | 1. Pałasz A,et al. Spider Neurotoxins as Modulators of NMDA Receptor Signaling. Neuromolecular Med. 2022 Sep;24(3):250-256. 2. Monge-Fuentes V, et al. Neuroactive compounds obtained from arthropod venoms as new therapeutic platforms for the treatment of neurological disorders. J Venom Anim Toxins Incl Trop Dis. 2015 Aug 8;21:31. doi: 10.1186/s40409-015-0031-x. 3. Fuchigami T,et al. Synthesis and brain regional distribution of [11C]NPS 1506 in mice and rat: an N-methyl-D-aspartate (NMDA) receptor antagonist. Biol Pharm Bull. 2003 Nov;26(11):1570-3. 4. Leoni MJ,et al. NPS 1506 attenuates cognitive dysfunction and hippocampal neuron death following brain trauma in the rat. Exp Neurol. 2000 Dec;166(2):442-9. |