| Description | D-NMAPPD ((1R,2R)-B13) is an acid ceramidase inhibitor. D-NMAPPD regulates the properties of NMDA receptor by enhancing the endogenous production of ceramides. D-NMAPPD has anticancer effecs [1] [2]. |
| In vitro | In rat hippocampal slices preincubated with the acid ceramidase inhibitor (ACI) d-NMAPPD, exhibits increased N-methyl-D-aspartate (NMDA) receptor-mediated field excitatory postsynaptic potentials (fEPSPs) in CA1 synapses [1]. |
| molecular weight | 422.56 |
| Molecular formula | C23H38N2O5 |
| CAS | 35922-06-6 |
| Storage | Powder: -20°C for 3 years | In solvent: -80°C for 1 year |