| Description | BMS-183920 is a diacid, potent angiotensin II receptor antagonist that improves Caco-2 cell permeability and in vivo oral absorption. The relative degree of hydrolysis (biological activation) and prodrug metabolism determines whether substantial improvements in bioavailability are achieved. |
| Synonyms | BMS-183920, BMS183920 |
| molecular weight | 449.46 |
| Molecular formula | C26H19N5O3 |
| CAS | 153072-33-4 |
| Storage | Powder: -20°C for 3 years | In solvent: -80°C for 1 year |
| References | 1. Obermeier MT, Chong S, Dando SA, Marino AM, Ryono DE, Starrett-Arroyo A, DiDonato GC, Warrack BM, White RE, Morrison RA. Prodrugs of BMS-183920: metabolism and permeability considerations. J Pharm Sci. 1996 Aug;85(8):828-33. PubMed PMID: 8863272. |