| Description | CYM50358 HCl is an S1P4 antagonist. |
| Synonyms | CYM50358 hydrochloride, CYM 50358 hydrochloride, CYM 50358 HCl, CYM-50358 hydrochloride, CYM-50358 HCl, CYM50358 HCl |
| molecular weight | 425.73 |
| Molecular formula | C20H19Cl3N2O2 |
| CAS | 1781750-72-8 |
| Storage | store at low temperature | Powder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice. |
| References | 1. Onuma T, Tanabe K, Kito Y, Tsujimoto M, Uematsu K, Enomoto Y, Matsushima-Nishiwaki R, Doi T, Nagase K, Akamatsu S, Tokuda H, Ogura S, Iwama T, Kozawa O, Iida H. Sphingosine 1-phosphate (S1P) suppresses the collagen-induced activation of human platelets via S1P4 receptor. Thromb Res. 2017 Aug;156:91-100. doi: 10.1016/j.thromres.2017.06.001. Epub 2017 Jun 2. PubMed PMID: 28609704. 2. Cencetti F, Bernacchioni C, Tonelli F, Roberts E, Donati C, Bruni P. TGFβ1 evokes myoblast apoptotic response via a novel signaling pathway involving S1P4 transactivation upstream of Rho-kinase-2 activation. FASEB J. 2013 Nov;27(11):4532-46. doi: 10.1096/fj.13-228528. Epub 2013 Aug 2. PubMed PMID: 23913862. |