| Description | Coniine hydrochloride, a polyketide-derived alkaloid, is poisonous to humans and animals. It is a nicotinic acetylcholine receptor antagonist, which leads to inhibition of the nervous system. |
| In vitro | γ-Coniine通过NADPH依赖的γ-Coniine还原酶转化为康尼因的过程较为顺畅。尽管Coniine因其毒性而臭名昭著，但关于其在食肉瓶子草中的生态作用尚无共识。最近，人们对Coniine在医疗上的用途，尤其是作为一种无成瘾性副作用的止痛药，重新产生了兴趣。 |
| molecular weight | 163.7 |
| Molecular formula | C8H18ClN |
| CAS | 15991-59-0 |
| Storage | Powder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice. |
| Solubility | DMSO: 27.5 mg/ml (167.99 mM) |
| References | 1. Hannu H , Heiko R . The killer of Socrates: Coniine and Related Alkaloids in the Plant Kingdom[J]. Molecules, 2017, 22(11):1962. |