| Description | CK2α-IN-1 is a selective non-ATP-competitive CK2α inhibitor with an IC50 of 7.0 µM and a Ki of 1.6 µM.CK2α-IN-1 exhibits potential anticancer activity and can be used in cancer research. |
| Target activity | CK2α:7.0 µM |
| molecular weight | 341.34 |
| Molecular formula | C16H11N3O4S |
| CAS | 443747-52-2 |
| Storage | Powder: -20°C for 3 years | In solvent: -80°C for 1 year |
| Solubility | DMSO: 55 mg/mL (161.13 mM) |
| References | 1. Bestgen B, et al. 2-Aminothiazole Derivatives as Selective Allosteric Modulators of the Protein Kinase CK2. Identification of an Allosteric Binding Site. J Med Chem. 2019 Feb 28;62(4):1803-1816. |