| Description | Citronellal ((±)-Citronellal) is a monoterpene predominantly formed by the secondary metabolism of plants, producing antithrombotic, antiplatelet, and antihypertensive activities. |
| In vitro | Citronellal（CT）（50、100和150 mg/kg）的给药以及洛伐他汀显著减小了高脂饮食加气球损伤和维生素D3喂养的动脉粥样硬化大鼠的颈动脉斑块尺寸，具有剂量依赖性。CT通过改善内皮功能障碍、增加细胞迁移、抑制氧化应激和炎症反应，在高脂饮食加气球损伤的大鼠血管内皮中展现了作用。此外，CT在动脉粥样硬化大鼠中下调了钠氢交换器1的蛋白水平[1]。 |
| Cell experiments | An AS model in carotid artery was induced by balloon injury and vitamin D3 injection in rats fed with a high-fat diet. The size of the carotid atherosclerotic plaque was determined by ultrasound, oil red, and hematoxylin-eosin staining. Endothelial function was assessed by measuring acetylcholine-induced vessel relaxation in an organ chamber[1]. |
| Synonyms | (±)-Citronellal, 香茅醛 |
| molecular weight | 154.25 |
| Molecular formula | C10H18O |
| CAS | 106-23-0 |
| Storage | Powder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice. |
| Solubility | DMSO: 30 mg/mL (194.49 mM) |
| References | 1. Lu J X , Guo C , Ou W S , et al. Citronellal prevents endothelial dysfunction and atherosclerosis in rats[J]. Journal of Cellular Biochemistry, 2018. 2. Araújo-Filho JV, Ribeiro WLC, André WPP,et al.Anthelmintic activity of Eucalyptus citriodora essential oil and its major component, citronellal, on sheep gastrointestinal nematodes.Rev Bras Parasitol Vet. 2019 Nov 25. pii: S1984-29612019005022101. |