Description | CEF3 acetate corresponds to aa 13-21 of the influenza A virus M1 protein. The matrix (M1) protein of influenza A virus is a multifunctional protein that plays essential structural and functional roles in the virus life cycle. |
In vitro | 流感A型病毒的基质(M1)蛋白是一种多功能蛋白,对病毒生命周期中的结构和功能起着至关重要的作用。它促进病毒的成熟并且是病毒粒子主要的蛋白质成分,在病毒外壳和整合膜蛋白以及基因组核糖核蛋白(RNPs)之间形成中间层。它还有助于控制RNPs的细胞内运输。这些作用主要通过与病毒和可能的细胞蛋白的蛋白-蛋白相互作用来介导[1]。流感病毒M1蛋白对于诱导vRNP核出口是必需的,但细胞的磷酸化是一个额外的因素。流感病毒M1蛋白对于病毒生命周期中的一个晚期事件至关重要——vRNPs从核到细胞质的转移[2]。 |
molecular weight | 971.16 |
Molecular formula | C44H78N10O14 |
Storage | keep away from moisture | Powder: -20°C for 3 years | In solvent: -80°C for 1 year |
Solubility | DMSO: 10 mM |
References | 1. Noton SL, et al. Identification of the domains of the influenza A virus M1 matrix protein required for NP binding, oligomerization and incorporation into virions. J Gen Virol. 2007 Aug;88(Pt 8):2280-90. |