| Description | Casein kinase 1δ-IN-1 (WAY-643895) is an inhibitor of casein kinase 1δ (CK1δ), which inhibits CK1δ. Casein kinase 1δ-IN-1 can be used in the study of neurodegenerative diseases such as Alzheimer's disease. |
| Synonyms | WAY-643895 |
| molecular weight | 229.26 |
| Molecular formula | C11H7N3OS |
| CAS | 851871-94-8 |
| Storage | Powder: -20°C for 3 years | In solvent: -80°C for 1 year |
| Solubility | DMSO: 3.85 mg/mL (16.78 mM), Sonication is recommended. |
| References | 1. Sheridan Joseph M, et al. Casein kinase 1δ inhibitors for the treatment of neurodegenerative disorders: World Intellectual Property Organization, WO2012080729[P]. 2. Knippschild U, et al. The role of the casein kinase 1 (CK1) family in different signaling pathways linked to cancer development. Onkologie. 2005;28(10):508-514. 3. Cheng HL, et al. Endogenous casein kinase I catalyzes the phosphorylation of the lens fiber cell connexin49. Eur J Biochem. 1999;263(1):276-286. |