| Description | CADD522 (MFCD00167693) is a potent inhibitor of runt-related transcription factor-2 (RUNX2)-DNA binding with an IC50 of 10 nM, with antitumor activity |
| In vitro | CADD522是一种强效的RUNX2-DNA结合抑制剂（ IC50为10 nM），具有抗肿瘤活性。 |
| Synonyms | MFCD00167693, 3-{[(3,4-二氯苯基)氨基]羰基}二环[2.2.1]庚-5-烯-2-羧酸 |
| molecular weight | 326.17 |
| Molecular formula | C15H13Cl2NO3 |
| CAS | 199735-88-1 |
| Storage | Powder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice. |
| Solubility | DMSO: 245 mg/mL (751.14 mM), Sonication is recommended. |
| References | 1. Kim MS, et al. Characterization of CADD522, a small molecule that inhibits RUNX2-DNA binding and exhibits antitumor activity. Oncotarget. 2017 Aug 10;8(41):70916-70940. |