| Description | BMS-986172 is an orally active, highly selective inhibitor of MGAT2, demonstrating inhibitory concentrations (IC50) of 4.6 nM for human MGAT2 (hMGAT2) and 20 nM for mouse MGAT2 (mMGAT2). It exhibits a half-life (T1/2) greater than 120 minutes in vitro and is known to decrease food intake and body weight. This compound is considered promising for the research of metabolic disorders, including obesity and non-alcoholic steatohepatitis (NASH) [1]. |
| molecular weight | 589.47 |
| Molecular formula | C24H22F7N7O3 |
| CAS | 1808258-99-2 |
| Storage | Powder: -20°C for 3 years | In solvent: -80°C for 1 year |