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Bisindolylmaleimide IV

CAS No.: 119139-23-0

Bisindolylmaleimide IV is a protein kinase C (PKC)cell permeable inhibitor( IC50 : 0.10 - 0.55 μM)
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Description Bisindolylmaleimide IV is a protein kinase C (PKC) cell permeable inhibitor( IC50 : 0.10 - 0.55 μM)
Target activity PKC:0.10 - 0.55 µM
molecular weight 327.34
Molecular formula C20H13N3O2
CAS 119139-23-0
Storage Powder: -20°C for 3 years | In solvent: -80°C for 1 year
Solubility DMSO: 3.27 mg/mL (10 mM), Sonication is recommended.
References 1. Toullec D , Pianetti P , Coste H , et al. The bisindolylmaleimide GF 109203X is a potent and selective inhibitor of protein kinase C.[J]. Journal of Biological Chemistry, 1991, 24(24):15771-15781. 2. Davis P D , Hill C H , Lawton G , et al. Inhibitors of protein kinase C. 1. 2,3-bisarylmaleimides[J]. Journal of Medicinal Chemistry, 1992, 35(1):177-184.