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BI-4916

CAS No.: 2244451-48-5

BI-4916 is a selective phosphoglycerate dehydrogenase (PHGDH) inhibitor that inhibits SSP and reduces the migration of c
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Description BI-4916 is a selective phosphoglycerate dehydrogenase (PHGDH) inhibitor that inhibits SSP and reduces the migration of cancer cells.BI-4916 can be used in the study of cancer and metabolic diseases.
Synonyms BI 4916, BI4916
molecular weight 527.42
Molecular formula C23H24Cl2N2O6S
CAS 2244451-48-5
Storage store at low temperature | Powder: -20°C for 3 years | In solvent: -80°C for 1 year
Solubility DMSO: 100 mg/mL (189.60 mM), Sonication is recommended.
References 1. Weinstabl H, et al. Intracellular Trapping of the Selective Phosphoglycerate Dehydrogenase (PHGDH) Inhibitor BI-4924 Disrupts Serine Biosynthesis. J Med Chem. 2019 Jul 31.