| Description | Beclobrate (Sgd 24774) is a novel orally available fibric acid derivative that has shown significant lipid and cholesterol-lowering activity in rodents and may be used in the study of primary hyperlipoproteinemia. |
| In vivo | 在正常饮食下,beclobrate 降低了总血浆胆固醇水平22-33.4%(10-50 mg/kg),胆固醇的减少主要发生在高密度脂蛋白(HDL)中[1]。 |
| Synonyms | Sgd 24774 |
| molecular weight | 346.85 |
| Molecular formula | C20H23ClO3 |
| CAS | 55937-99-0 |
| Storage | Powder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice. |
| References | 1. C Manzoni, et al. Differential effects of beclobrate on lipid/lipoprotein distribution in normal and hypercholesterolemic rats. Eur J Pharmacol. 1990 Nov 6;190(1-2):39-49. |