| Description | B7/CD28 interaction inhibitor 1 (CTLA-4 inhibitor) is a potent CTLA-4 inhibitor. |
| Target activity | B7.1-CD28 interaction:50 nM (IC50) |
| Synonyms | CTLA-4 inhibitor |
| molecular weight | 427.35 |
| Molecular formula | C21H13F4N5O |
| CAS | 635324-72-0 |
| Storage | Powder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice. |
| Solubility | DMSO: 85 mg/mL (198.90 mM) |
| Citations | 1. Zhao Y, Hao C, Li M, et al. PD-1/PD-L1 inhibitor ameliorates silica-induced pulmonary fibrosis by maintaining systemic immune homeostasis. Biomedicine & Pharmacotherapy. 2022, 148: 112768. |