| Description | Azide-PEG3-Desthiobiotin is a PROTAC linker belonging to the PEG class and can be used to synthesize PROTAC molecules. |
| In vitro | PROTACs通过连接器连接两个不同的配体；一个是E3泛素连接酶的配体，另一个是目标蛋白质的配体。PROTACs利用细胞内的泛素-蛋白酶体系统，有选择性地降解目标蛋白质。[1] |
| Synonyms | Azide-PEG3-Desthiobiotin |
| molecular weight | 414.5 |
| Molecular formula | C18H34N6O5 |
| CAS | 1426828-06-9 |
| Storage | store at low temperature|Powder: -20°C for 3 years | In solvent: -80°C for 1 year |
| Solubility | DMSO: 100 mg/mL (241.25 mM), Sonication is recommended. H2O: 100 mg/mL (241.25 mM), Sonication is recommended. |
| References | 1. An S, et al. Small-molecule PROTACs: An emerging and promising approach for the development of targeted therapy drugs. EBioMedicine. 2018 Oct;36:553-562 |