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Aspartyl-alanyl-diketopiperazine

CAS No.: 110954-19-3

Aspartyl-alanyl-diketopiperazine (DA-DKP) is a known immunomodulatory molecule from the N terminus of human albumin.
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Description Aspartyl-alanyl-diketopiperazine (DA-DKP) is a known immunomodulatory molecule from the N terminus of human albumin.
In vitro Ampion能够通过涉及T-淋巴细胞无能症的分子通路调节炎症性免疫反应[1]。
Synonyms DA-DKP
molecular weight 186.17
Molecular formula C7H10N2O4
CAS 110954-19-3
Storage Powder: -20°C for 3 years | In solvent: -80°C for 1 year
Solubility DMSO: 100 mg/mL (537.14 mM), Sonication is recommended.
References 1. Shimonkevitz R, et al. A diketopiperazine fragment of human serum albumin modulates T-lymphocyte cytokine production through rap1. J Trauma. 2008 Jan;64(1):35-41. 2. Bar-Or D, et al. Dipeptidyl peptidase IV activity in commercial solutions of human serum albumin. Anal Biochem. 2013 Oct 1;441(1):13-7.