Description | Aspartyl-alanyl-diketopiperazine (DA-DKP) is a known immunomodulatory molecule from the N terminus of human albumin. |
In vitro | Ampion能够通过涉及T-淋巴细胞无能症的分子通路调节炎症性免疫反应[1]。 |
Synonyms | DA-DKP |
molecular weight | 186.17 |
Molecular formula | C7H10N2O4 |
CAS | 110954-19-3 |
Storage | Powder: -20°C for 3 years | In solvent: -80°C for 1 year |
Solubility | DMSO: 100 mg/mL (537.14 mM), Sonication is recommended. |
References | 1. Shimonkevitz R, et al. A diketopiperazine fragment of human serum albumin modulates T-lymphocyte cytokine production through rap1. J Trauma. 2008 Jan;64(1):35-41. 2. Bar-Or D, et al. Dipeptidyl peptidase IV activity in commercial solutions of human serum albumin. Anal Biochem. 2013 Oct 1;441(1):13-7. |