Argipressin acetate (113-79-1(free base)) Bioactivity,Chemical Properties,Storage & Solubility Information Pathways-PeptideDB

Description	Vasopressin acetate is a peptide hormone with vasoconstrictive and antidiuretic activities that binds to the vascular arginine vasopressin receptor, V1, with Kd values of 1.31 and 1.44 nM in A7r5 rat aortic smooth muscle cells and neonatal rat cardiomyocytes, respectively
In vitro	Vasopressin 通过cAMP-PKA和Ca(2+)信号途径在结肠中促进NKCC2的磷酸化水平增加。通过 Vasopressin 刺激，结合 Vasopressin /cAMP和Ca(2+)途径的活性增强，NKCC2在结肠中的表达和磷酸化水平得到上调[1]。
molecular weight	1144.28
Molecular formula	C48H69N15O14S2
CAS	83968-48-3
Storage	keep away from moisture \| Powder: -20°C for 3 years \| In solvent: -80°C for 1 year \| Shipping with blue ice.
Solubility	H2O: 360 mg/mL (332.03 mM)
References	1. Xue H , Tang X . Effect of vasopressin on Na+–K+–2Cl? cotransporter (NKCC) and the signaling mechanisms on the murine late distal colon[J]. European Journal of Pharmacology, 2016, 771:241-246. 2. Yao Y , Fu L Y , Zhang X , et al. Vasopressin and oxytocin excite MCH neurons, but not other lateral hypothalamic GABA neurons[J]. AJP Regulatory Integrative and Comparative Physiology, 2012, 302(7):R815-24.

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