| Description | Arg-Gly-Asp-Cys acetate inhibits platelet aggregation and fibrinogen binding. Arg-Gly-Asp-Cys acetate is the binding motif of fibronectin to cell adhesion molecules. |
| In vitro | Arg-Gly-Asp-Cys acetate功能化壳聚糖衍生物通过增强成纤维细胞的增殖和粘附,表现出体外促进伤口愈合的特性。Arg-Gly-Asp-Cy sacetate-DAH-CMTMC促进了细胞生长,并与对照细胞相比,提高了细胞增殖率。将Arg-Gly-Asp-Cy sacetate固定在DAH-CMTMC上,其在壳聚糖衍生物中的含量约为15.3μg/mg。经Arg-Gly-Asp-Cys acetate功能化的壳聚糖可能促进伤口愈合,提高了细胞活性(存活率>140%)[1]。 |
| Synonyms | Arg-Gly-Asp-Cys acetate(109292-46-8 free base), RGDC acetate |
| molecular weight | 509.54 |
| Molecular formula | C17H31N7O9S |
| Storage | store at low temperature,keep away from moisture | Powder: -20°C for 3 years | In solvent: -80°C for 1 year |
| References | 1. Patrulea V, et al. Peptide-decorated chitosan derivatives enhance fibroblast adhesion and proliferation in wound healing. Carbohydr Polym. 2016 May 20;142:114-23. |