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1,8-Diazafluoren-9-one

CAS No.: 54078-29-4

1,8-Diazafluoren-9-one (DFO) is used to find fingerprints on porous surfaces.
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Description 1,8-Diazafluoren-9-one (DFO) is used to find fingerprints on porous surfaces.
In vitro 1,8-diazafluoren-9-one(DFO)因其出色的增强特性而在法医领域被广泛使用,主要用于增强存留在多孔表面上的潜在指纹,其通过与表皮排泄物中的氨基酸反应,形成荧光产物以实现此目的。
Synonyms DFO, 1,8-二氮杂-9-芴酮, 9H-1,8-Diazafluoren-9-one
molecular weight 182.18
Molecular formula C11H6N2O
CAS 54078-29-4
Storage keep away from direct sunlight | Powder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice.
Solubility DMSO: 5 mg/mL (27.45 mM), Sonication is recommended.
References 1. D'Elia V, et al. Evaluation and comparison of 1,2-indanedione and 1,8-diazafluoren-9-one solutions for the enhancement of latent fingerprints on porous surfaces. Forensic Sci Int. 2015 Sep;254:205-14. 2. Huang L, Liu Z, Liu H, et al. Iron Overload Impairs Bone Marrow Mesenchymal Stromal Cells from Higher-Risk MDS Patients by Regulating the ROS-Related Wnt/β-Catenin Pathway[J]. Stem cells international. 2020, 2020. 3. Huang S, Cao B, Zhang J, et al. Induction of ferroptosis in human nasopharyngeal cancer cells by cucurbitacin B: molecular mechanism and therapeutic potential[J]. Cell Death & Disease . 2021, 12(3): 1-13. 4. Bebber C M, Thomas E S, Chen Z, et al. Ferroptosis response segregates small cell lung cancer (SCLC) neuroendocrine subtypes[J]. Nature Communications. 2021
Citations 1. Peng H, Zhang X, Yang P, et al. Defect self-assembly of metal-organic framework triggers ferroptosis to overcome resistance. Bioactive Materials. 2021 2. Bebber C M, Thomas E S, Chen Z, et al. Ferroptosis response segregates small cell lung cancer (SCLC) neuroendocrine subtypes. Nature Communications. 2021 Apr 6;12(1):2048. doi: 10.1038/s41467-021-22336-4. 3. Chen G, Fan X, Li Y, et al. Promoter aberrant methylation status of ADRA1A is associated with hepatocellular carcinoma. Epigenetics. 2020, 15(6-7): 684-701 4. Luo Y, Gao X, Zou L, et al. Bavachin Induces Ferroptosis through the STAT3/P53/SLC7A11 Axis in Osteosarcoma Cells. Oxidative Medicine and Cellular Longevity. 2021 5. Jiang H, Wang C, Zhang A, et al. ATF4 protects against sorafenib-induced cardiotoxicity by suppressing ferroptosis. Biomedicine & Pharmacotherapy. 2022, 153: 113280 6. Huang S, Cao B, Zhang J, et al. Induction of ferroptosis in human nasopharyngeal cancer cells by cucurbitacin B: molecular mechanism and therapeutic potential. Cell Death & Disease. 2021, 12(3): 1-13. 7. Tan Q, Fang Y, Peng X, et al. A new ferroptosis inhibitor, isolated from Ajuga nipponensis, protects neuronal cells via activating NRF2-antioxidant response elements (AREs) pathway. Bioorganic Chemistry. 2021: 105177. 8. Peng X, Tan Q, Wu L, et al. Ferroptosis Inhibitory Aromatic Abietane Diterpenoids from Ajuga decumbens and Structural Revision of Two 3, 4-Epoxy Group-Containing Abietanes. Journal of Natural Products. 2022 9. Huang L, Liu Z, Liu H, et al Iron Overload Impairs Bone Marrow Mesenchymal Stromal Cells from Higher-Risk MDS Patients by Regulating the ROS-Related Wnt/β-Catenin Pathway. Stem Cells International. 2020 10. Jiang X, Teng X, Shi H, et al.Discovery and optimization of olanzapine derivatives as new ferroptosis inhibitors.Bioorganic Chemistry.2023: 106393. 11. Tan Q, Wu D, Lin Y, et al.Identifying eleven new ferroptosis inhibitors as neuroprotective agents from FDA-approved drugs.Bioorganic Chemistry.2024: 107261.