| Description | APY0201 is a effective, highly specific, ATP-competitive PIKfyve inhibitor (IC50: 5.2 nM). It can interrupt the conversion of phosphatidylinositol 3-phosphate (PtdIns3P) to PtdIns(3, 5)P2. |
| Target activity | PIKfyve:5.2 nM |
| molecular weight | 413.48 |
| Molecular formula | C23H23N7O |
| CAS | 1232221-74-7 |
| Storage | Powder: -20°C for 3 years | In solvent: -80°C for 1 year |
| Solubility | DMSO: 1 mg/ml, Sonication is recommended. |
| References | 1. Hayakawa N, et al. Bioorg Med Chem. 2014 Jun 1;22(11):3021-9. |