| Description | The Antitrypanosomal agent 7 (compound 18c) is a potent anti-trypanosome agent and shows good ADME properties. The Antitrypanosomal agent 7 was more than two-fold more active against T. brucei (IC50: 0.71 μM) than Nifurtimox. Antitrypanosomal agent 7 has a strong interaction with DNA and can selectively bind to AT-rich DNA. |
| molecular weight | 407.51 |
| Molecular formula | C23H29N5O2 |
| CAS | 2492436-38-9 |
| Storage | Powder: -20°C for 3 years | In solvent: -80°C for 1 year |