| Description | Antiproliferative agent-16 (Antiproliferative agent-16) is an indolyl hydrazide-hydrazone compound with anticancer activity. Antiproliferative agent-16 exhibits specificity toward breast cancer cells (IC50 of 6.94 μM for MCF-7 cells). |
| In vitro | Antiproliferative agent-16 对DU145、LNCaP、MDA-MB231、MCF7和PaCa2癌细胞表现出细胞毒性，其半抑制浓度（IC50）值分别为115.1 μM、51.63 μM、300.8 μM、6.94 μM和91.18 μM [1]。 |
| Synonyms | Antiproliferative agent-16 |
| molecular weight | 277.32 |
| Molecular formula | C17H15N3O |
| CAS | 15641-17-5 |
| Storage | Powder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice. |
| Solubility | DMSO: 50 mg/mL (180.3 mM) |
| References | 1. Swapna Sundaree, et al. Synthesis and anticancer activity study of indolyl hydrazide-hydrazones. Med Chem Res 25, 941-950 (2016). |