| Description | Antiproliferative agent-15 is a reagent with anticancer activity. Antiproliferative agent-15 showed antiproliferative activity against human colon cancer (HCT116 and HCT15) and brain cancer (LN-229 and GBM-10). |
| In vitro | Antiproliferative agent-15针对人类结肠癌细胞系（HCT116和HCT15）及脑癌细胞系（LN-229和GBM-10）显示出抗增殖活性，其IC50值分别为8.3 μM、4.8 μM、18.3 μM和12 μM [1]。 |
| Target activity | GBM10:12 μM, LN229:18.3 μM, HCT116 cells:8.3 μM, HCT15 cells:4.8 μM |
| molecular weight | 282.36 |
| Molecular formula | C16H14N2OS |
| CAS | 19819-18-2 |
| Storage | Powder: -20°C for 3 years | In solvent: -80°C for 1 year |
| Solubility | DMSO: Slightly soluble |
| References | 1. Haneen Amawi, et al. Thienopyrimidine derivatives exert their anticancer efficacy via apoptosis induction, oxidative stress and mitotic catastrophe. Eur J Med Chem. 2017 Sep 29;138:1053-1065. |