| Description | Anticonvulsant agent 2 is a potent orally active anticonvulsant that has shown antiepileptic activity in a model of drug-resistant epilepsy. |
| In vivo | Anticonvulsant agent 2（50 mg/kg，p.o.）在大鼠中降低了运动活动，抑制率达21.01%。[1] 同一化合物在大鼠体内展现了抗癫痫活性，其抑制率为24.45%。[1] |
| molecular weight | 332.83 |
| Molecular formula | C21H17ClN2 |
| CAS | 75220-84-7 |
| Storage | Powder: -20°C for 3 years | In solvent: -80°C for 1 year |
| Solubility | DMSO: 112.5 mg/mL (338.0 mM ), Sonication and heating to 60℃ are recommended. |
| References | 1. Verma R,et al. Design, synthesis and neuropharmacological evaluation of new 2,4-disubstituted-1,5-benzodiazepines as CNS active agents. Bioorg Chem. 2020 ; 101:104010. |