| Description | AMN082 free base is a metabotropic glutamate receptor 7 allosteric agonist. |
| In vivo | MN082 减缓了通过涉及小鼠中的 mGluR7s 机制,可卡因和吗啡敏感化的发展和表达,以及相互的交叉敏感化。 |
| Synonyms | AMN082 |
| molecular weight | 392.54 |
| Molecular formula | C28H28N2 |
| CAS | 83027-13-8 |
| Storage | Powder: -20°C for 3 years | In solvent: -80°C for 1 year |
| Solubility | DMSO: 3.93 mg/ml (10 mM) |
| References | 1. 1. Marszalek, M, Komsta, et al. AMN082, a metabotropic glutamate receptor 7 allosteric agonist, attenuates locomotor sensitization and cross-sensitization induced by cocaine and morphine in mice[J]. Progress in Neuro Psychopharmacology & Biological Psychiatry An International Research Review & News Journal, 2015. |