| Description | AMG131 (CHS 131) , is a novel, non-thiazolidinedione (TZD), selective peroxisome proliferator-activated receptor (PPAR)gamma modulator, which can be used for the treatment of type 2 diabetes mellitus (non-insulin dependent diabetes) |
| Synonyms | INT-131, AMG-131, CHS 131 |
| molecular weight | 514.21 |
| Molecular formula | C21H12Cl4N2O3S |
| CAS | 315224-26-1 |
| Storage | Powder: -20°C for 3 years | In solvent: -80°C for 1 year |
| Solubility | DMSO: 27.5 mg/mL (53.48 mM) |
| References | 1. Kintscher U , Goebel M . INT-131, a PPARgamma agonist for the treatment of type 2 diabetes.[J]. Curr Opin Investig Drugs, 2009, 10(4):381-387. |