| Description | α-Amylase-IN-1 is an α-Amylase inhibitor (IC50: 0.5509 μM). α-Amylase-IN-1 has antioxidant activity with an IC50 value of 53.49 μM for scavenging of DPPH free radicals, and can be used in the study of diabetes and oxidative stress-related diseases. |
| Target activity | α-amylase:0.5509 μM, DPPH:53.49 μM |
| molecular weight | 310.35 |
| Molecular formula | C18H18N2O3 |
| CAS | 148404-10-8 |
| Storage | Powder: -20°C for 3 years | In solvent: -80°C for 1 year |
| Solubility | DMSO: 50 mg/mL (161.11 mM) |
| References | 1. Ali A, et al. Dihydropyrazole Derivatives Act as Potent α-Amylase Inhibitors and Free Radical Scavengers: Synthesis, Bioactivity Evaluation, Structure-Activity Relationship, ADMET, and Molecular Docking Studies. ACS Omega. 2023;8(23):20412-20422. |