| Description | Alovudine (3'-Deoxy-3'-fluorothymidine) is a marker of DNA synthesis. Alovudine is less susceptible to inflammatory changes than 18F-Fluorodeoxyglucose (FDG) and is a better biomarker in pancreatic cancer. |
| Synonyms | 3'-Deoxy-3'-fluorothymidine, 3'-脱氧-3-氟胸苷 |
| molecular weight | 244.22 |
| Molecular formula | C10H13FN2O4 |
| CAS | 25526-93-6 |
| Storage | Powder: -20°C for 3 years | In solvent: -80°C for 1 year |
| Solubility | DMSO: 55 mg/mL (225.2 mM) |
| References | 1. Ghosn, J., Quinson, A., Sabo, N., Cotte, L., Piketty, C., & Dorléacq, N. et al. (2007). Antiviral activity of low-dose alovudine in antiretroviral-experienced patients: results from a 4-week randomized, double-blind, placebo-controlled dose-ranging trial. HIV Medicine, 8(3), 142-147. doi: 10.1111/j.1468-1293.2007.00444.x |