Description | Alloimperatorin (Prangenidin) exhibits in vitro antitumor activity in HL-60 acute myeloid leukemia cancer cells via inducing apoptosis, cell cycle disruption and inhibition of cell migration. It photosensitizes efficiently the hemolysis of erythrocytes. |
In vitro | 细胞毒性效果通过MTT实验进行了展示。使用荧光显微镜技术及流式细胞仪来评估Alloimperatorin epoxide对细胞凋亡和细胞周期的影响。为研究化合物对癌细胞迁移的影响,进行了体外创伤愈合实验[1]。 |
Synonyms | Prangenidin, 别欧前胡素 |
molecular weight | 270.28 |
Molecular formula | C16H14O4 |
CAS | 642-05-7 |
Storage | Powder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice. |
Solubility | DMSO: 50 mg/mL (184.99 mM) |
References | 1. Alloimperatorin and its epoxide derivative exhibit in vitro antitumor activity in HL-60 acute myeloid leukemia cancer cells via inducing apoptosis, cell cycle disruption and inhibition of cell migrationBangladesh Journal of Pharmacology, 2016, 11(1):194. |