| Description | Alisol F is a natural product from Alisma plantago-aquatica Linn and has many activities. |
| In vitro | Alisol F通过体内外抑制MAPK、STAT3和NF-κB的激活，展现了抗炎作用和肝脏保护能力，它抑制了iNOS的诱导[1]。Alisol F还在体外对乙型肝炎病毒(HBV)表面抗原(HBsAg)的分泌表现出抑制作用，具体是在Hep G2.2.15细胞线上，IC50值为0.6 μM；同样，对HBV e抗原(HBeAg)的分泌也显示出抑制活性(IC50: 8.5 μM)[2]。 |
| Synonyms | 泽泻醇 F, 泽泻醇F |
| molecular weight | 488.7 |
| Molecular formula | C30H48O5 |
| CAS | 155521-45-2 |
| Storage | Powder: -20°C for 3 years | In solvent: -80°C for 1 year |
| Solubility | DMSO: Soluble |
| References | 1. H Matsuda, et al. Effects of sesquiterpenes and triterpenes from the rhizome of Alisma orientale on nitric oxide production in lipopolysaccharide-activated macrophages: absolute stereostructures of alismaketones-B 23-acetate and -C 23-acetate. Bioorg Med Chem Lett. 1999 Nov 1;9(21):3081-6. 2. Zhi-Yong Jiang, et al. A new triterpene and anti-hepatitis B virus active compounds from Alisma orientalis. Planta Med. 2006 Aug;72(10):951-4. |