| Description | ADAMTS-5-IN-3 (Example 37-2) is a potent inhibitor of ADAMTS-5 (IC50: 8 nM) and ADAMTS-4 (IC50: 12 nM).ADAMTS-5-IN-3 can be used to study diseases associated with cartilage degeneration or disruption of cartilage homeostasis, particularly osteoarthrosis and/or rheumatoid arthritis. |
| molecular weight | 424.32 |
| Molecular formula | C20H23Cl2N3O3 |
| CAS | 2688733-96-0 |
| Storage | Powder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice. |