| Description | ABD56 inhibits osteoclast formation and activity in vitro and in vivo. |
| Synonyms | ABD-56, ABD 56 |
| molecular weight | 270.32 |
| Molecular formula | C17H18O3 |
| CAS | 521294-19-9 |
| Storage | Powder: -20°C for 3 years | In solvent: -80°C for 1 year |
| References | 1. Idris AI, Mrak E, Greig I, Guidobono F, Ralston SH, van 't Hof R. ABD56 causes osteoclast apoptosis by inhibiting the NFkappaB and ERK pathways. Biochem Biophys Res Commun. 2008 Jun 20;371(1):94-8. doi: 10.1016/j.bbrc.2008.04.014. Epub 2008 Apr 14. Erratum in: Biochem Biophys Res Commun. 2010 Apr 30;395(2):289. Idris, Aymen [corrected to Idris, Aymen I]. PubMed PMID: 18413146. 2. Idris AI, Greig IR, Bassonga-Landao E, Ralston SH, van 't Hof RJ. Identification of novel biphenyl carboxylic acid derivatives as novel antiresorptive agents that do not impair parathyroid hormone-induced bone formation. Endocrinology. 2009 Jan;150(1):5-13. doi: 10.1210/en.2008-0998. Epub 2008 Sep 4. PubMed PMID: 18772231. |