| Description | 7-keto-deoxycholic acid is converted from Lactobacillus and Bifidobacterium with specific condition and from cholic acid in vitro. |
| In vitro | 在厌氧培养条件下，类似Eubacterium lentum的c-25将3.7%的胆酸(2 mM)转化为7-keto-deoxycholic acid，并将1.1%的胆酸(150 mg/mL)转化为7-keto-deoxycholic acid[1]。 |
| Synonyms | 7-Keto-3alpha,12alpha-dihydroxycholanic acid |
| molecular weight | 406.56 |
| Molecular formula | C24H38O5 |
| CAS | 911-40-0 |
| Storage | Powder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice. |
| Solubility | 10% DMSO+40% PEG300+5% Tween-80+45% Saline: 10 mg/mL, Sonication is recommended. DMSO: 100 mg/mL (245.9 mM), Sonication is recommended. |
| References | 1. Takahashi T, et al. Absence of cholic acid 7 alpha-dehydroxylase activity in the strains of Lactobacillus and Bifidobacterium. J Dairy Sci. 1994 Nov;77(11):3275-86. 2. Sutherland JD, et al. The metabolism of primary, 7-oxo, and 7 beta-hydroxy bile acids by Clostridium absonum. J Lipid Res. 1982 Jul;23(5):726-32. 3. Morotomi M, Kawai Y, Mutai M. Intestinal microflora and bile acids. In vitro cholic acid transformation by mixed fecal culture of rats. Microbiol Immunol. 1979;23(9):839-47. |