| Description | 6-Methoxykaempferol is a flavonoid found in brazilian propolis. 6-Methoxykaempferol has anti-proliferative activity against cancer cells, neuroprotective effects on isolated rat brain synaptosomes and reduces glutathione levels. 6-Methoxykaempferol exhibits some lipase activity and may be used in the treatment of cachexia. 6-Methoxykaempferol exhibits some lipase activity and can be used in the treatment of cachexia. |
| In vitro | 6-Methoxykaempferol (0-200 µM ; 24 h) 对癌细胞展示了抗增殖效应，其IC50分别为DLD-1细胞101.8 µM，MCF-7细胞>200 µM，以及A549细胞125.1 µM。[1] |
| Target activity | A549 cells:125.1 µM, DLD-1 cells:101.8 µM, MCF-7 cells:>200 µM |
| molecular weight | 316.26 |
| Molecular formula | C16H12O7 |
| CAS | 32520-55-1 |
| Storage | store at low temperature,keep away from direct sunlight | Powder: -20°C for 3 years | In solvent: -80°C for 1 year |
| References | 1. Mitsui T, et al. Chemical constituents of Brazilian Propolis from the state of Bahia and their growth inhibitory activities against cancer cells. Biosci Biotechnol Biochem. 2018 ; 82(3):417-421. 2. Lee YG, et al. 6-Methoxyflavonols from the aerial parts of Tetragonia tetragonoides (Pall.) Kuntze and their anti-inflammatory activity. Bioorg Chem. 2019 ; 88:102922. |