| Description | 6-CFDA (6-Carboxyfluorescein diacetate) is fluorescent polyanionic probe that used to measure changes in intracellular pH (pHi) and processes such as dendrimer aggregation and absorption. |
| Synonyms | 6-羧基荧光素二醋酸, 6-Carboxyfluorescein diacetate |
| molecular weight | 460.39 |
| Molecular formula | C25H16O9 |
| CAS | 3348-03-6 |
| Storage | keep away from direct sunlight | Powder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice. |
| Solubility | DMSO: 97 mg/mL (210.69 mM), Sonication is recommended. |
| References | 1. Babcock DF. Examination of the intracellular ionic environment and of ionophore action by null point measurements employing the fluorescein chromophore. J Biol Chem. 1983 May 25;258(10):6380-9. 2. Graber ML, et al. Characteristics of fluoroprobes for measuring intracellular pH. Anal Biochem. 1986 Jul;156(1):202-12. 3. Bonizzoni M, et al. PAMAM dendrimer-induced aggregation of 5(6)-carboxyfluorescein. J Org Chem. 2012 Feb 3;77(3):1258-66. |