| Description | 3,4-Dihydroxyflavone Acts as an Antioxidant and Antiapoptotic Agent . |
| In vitro | 使用3,4-DHF可以增加ICM细胞数量并减少细胞内ROS产生和凋亡细胞数量。当O(2)张力从20%(高张力)降至5%(低张力)时,胚胎发育率不论是否接受3,4-DHF处理都会翻倍[1]。 |
| Cell experiments | Blastocyst development, total cell and inner cell mass (ICM) numbers, intracellular levels of reactive oxygen species (ROS), apoptotic indices and gene expression levels were examined before and after treatment of day 2 bovine embryos (≥2-4 cells) with various concentrations of 3,4-DHF or SOD for 6 days[1]. |
| molecular weight | 254.24 |
| Molecular formula | C15H10O4 |
| CAS | 4143-64-0 |
| Storage | Powder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice. |
| Solubility | DMSO: 20 mg/mL (78.67 mM) |
| References | 1. Lee K S , Kim E Y , Jeon K , et al. 3,4-Dihydroxyflavone Acts as an Antioxidant and Antiapoptotic Agent to Support Bovine Embryo Development In Vitro[J]. Journal of Reproduction & Development, 2011, 57(1):127-134. 2. Hossain M K , Choi H Y , Hwang J S , et al. Antiviral activity of 3,4’-dihydroxyflavone on influenza a virus[J]. Journal of Microbiology, 2014, 52(6):521-526. |